Article

<em>In silico</em> Prediction and Cytotoxicity Evaluation of siRNAs Targeting Conserved Regions of MERS-CoV in Cell Culture

2019-02-28

Abstract excerpt

The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was isolated in 2012 and is well known to cause the respiratory syndrome. The orf1ab gene is known to mediate MERS-CoV replication. In this study, we have discussed the in silico prediction of potential siRNAs targeting MERS-CoV-orf1ab gene for antiviral therapeutics. To identify the potential siRNAs, various factors were considered. We have excluded the...

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Literature Corpus work: 6de20901-6890-58aa-897c-334834f53d2c
DOI: 10.20944/preprints201902.0268.v1

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