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In silico prediction and experimental validation of siRNAs targeting ORF1ab of MERS-CoV in Vero cell line

26 Nov 2020

Abstract excerpt

The Middle East Respiratory Syndrome Coronavirus is well known to cause respiratory syndrome and this virus was identified and isolated for the first time from Jeddah, Saudi Arabia in 2012 from infected patient. In this report, we have conducted the in-silico prediction, designing and evaluation of siRNAs targeting Middle East Respiratory Syndrome Coronavirus orf1ab gene to inhibit the virus replication. By using...

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PMID: 33519276
DOI: 10.1016/j.sjbs.2020.11.066

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