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Baseline expression of immune gene modules in blood is associated with primary response to anti-TNF therapy in Crohn’s disease patients

2023-04-24

Abstract excerpt

<h4>Background and Aims</h4> Anti-TNF therapy is widely used for treatment of inflammatory bowel disease (IBD), yet many patients are primary non-responders (PNR), failing to respond to induction therapy. We aimed to identify blood gene expression differences between primary responders (PR) and primary non-responders to anti-TNF monoclonal antibodies (infliximab and adalimumab); and to predict response status from...

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Literature Corpus work
6dda748e-092a-5288-a5b5-7c9180143872
DOI
10.1101/2023.04.19.23288234
Open publication

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Baseline expression of immune gene modules in blood is associated with primary response to anti-TNF therapy in Crohn’s disease patientsDOI 10.1101/2023.04.19.23288234
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