Article

A blood-based prognostic biomarker in inflammatory bowel disease

2019-01-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> We have previously described a prognostic transcriptional signature in CD8 T cells that separates inflammatory bowel disease (IBD) patients into 2 phenotypically-distinct subgroups, which we termed IBD1 and IBD2. Here we sought to develop a blood-based prognostic test that could identify these patient subgroups without the need for cell separation, and thus be suitable for ro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8855cce8-8223-5cee-9b34-178cd4460b34
DOI: 10.1101/535153

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A blood-based prognostic biomarker in inflammatory bowel diseaseDOI 10.1101/535153Read

Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling.Semantic proximity Read

Blood transcriptomics identifies FEZ1 as a novel non-invasive diagnostic biomarker for inflammatory bowel diseaseSemantic proximity Read

Development of a 32-gene signature using machine learning for accurate prediction of inflammatory bowel diseaseSemantic proximity Read

The use of prognostic factors in inflammatory bowel diseases.Semantic proximity Read

Integrative biomarker discovery and immune profiling for ulcerative colitis: a multi-methodological approachSemantic proximity Read

Deciphering Diagnostic Biomarkers and Immune Infiltration Characteristics in Ulcerative Colitis and Inflammatory Bowel Disease Through Genetic ProfilingSemantic proximity Read

Multi-omics data integration identifies novel biomarkers and patient subgroups in inflammatory bowel diseaseSemantic proximity Read

Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel diseaseSemantic proximity Read

Molecular Classification of Crohn's Disease and Ulcerative Colitis Patients Using Transcriptional Profiles in Peripheral Blood Mononuclear CellsSemantic proximity Read

Discovery of a simple two-gene expression biomarker in whole blood predictive of the need for treatment escalation in inflammatory bowel diseaseSemantic proximity Read

Molecular Profiling of Inflammatory Bowel Disease: Is It Ready for Use in Clinical Decision-Making?Semantic proximity Read

Supervised Machine Learning Classifies Inflammatory Bowel Disease Patients by Subtype Using Whole Exome Sequencing DataSemantic proximity Read