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Metabolic remodeling by the PD-L1 inhibitor BMS-202 significantly inhibits cell malignancy in human glioblastoma

2023-09-18

Abstract excerpt

Recent crystallographic studies have shown that BMS-202, a small molecule compound with a methoxy-1-pyridine chemical structure, interacts well with PD-L1 dimerization. However, its roles and mechanisms of BMS-202 in glioma have not yet been reported. The aims of this work were to study BMS-202 antitumor activity and its underlying mechanisms in glioma. In the study, the multi-omics and bioinformatics tools, a ser...

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Literature Corpus work
6d53bec5-57f3-5cf4-9698-e9f763547b3f
DOI
10.21203/rs.3.rs-3247198/v1
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Metabolic remodeling by the PD-L1 inhibitor BMS-202 significantly inhibits cell malignancy in human glioblastomaDOI 10.21203/rs.3.rs-3247198/v1
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