Article

Comprehensive Analysis of Mutation-Based and Expressed Genes-Based Pathways in Head and Neck Squamous Cell Carcinoma

2020-07-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Over- or under-expression of mRNA results from genetic alterations. Comprehensive pathway analyses based on mRNA expression are as important as single gene level mutations. This study aimed to compare the mutation-and mRNA expression-based signaling pathways in head and neck squamous cell carcinoma (HNSCC), and to match these with potential drug or druggable pat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 89d808a7-7263-5377-8447-5c53b1ad3d13
DOI: 10.21203/rs.3.rs-41520/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comprehensive Analysis of Mutation-Based and Expressed Genes-Based Pathways in Head and Neck Squamous Cell CarcinomaDOI 10.21203/rs.3.rs-41520/v1Read

Identification of Potential Biomarkers and Survival Analysis for Head and Neck Squamous Cell Carcinoma Using Bioinformatics Strategy: A Study Based on TCGA and GEO DatasetsSemantic proximity Read

Data mining on identifying diagnosis and prognosis biomarkers in head and neck squamous carcinomaSemantic proximity Read

Identifying Biomarkers and Therapeutic Targets by Multiomic Analysis for HNSCC: Precision Medicine and Healthcare ManagementSemantic proximity Read

Sequencing the head and neck cancer genome: implications for therapy.Semantic proximity Read

The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapiesSemantic proximity Read

Massive parallel sequencing of head and neck conventional squamous cell carcinomas: A comprehensive review.Semantic proximity Read

Investigating the Feasibility of Targeted Next-Generation Sequencing to Guide the Treatment of Head and Neck Squamous Cell Carcinoma.Semantic proximity Read

Identiﬁcation of Key Genes and Pathways in Tongue Squamous Cell Carcinoma Using Bioinformatics AnalysisSemantic proximity Read

Identification of key genes for HNSCC from public databases using bioinformatics analysisSemantic proximity Read

Screening key lncRNAs with diagnostic and prognostic value for head and neck squamous cell carcinoma based on machine learning and mRNA-lncRNA co-expression network analysisSemantic proximity Read

Comprehensive Bioinformatic Analysis for Identification of Crucial Genes and Signaling Transduction Pathways in Head and Neck Squamous Cell CarcinomaSemantic proximity Read

Genomic analysis of head and neck squamous cell carcinoma cell lines and human tumors: a rational approach to preclinical model selection.Semantic proximity Read