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Switching from Complement Inhibitors in AQP4-IgG–Positive NMOSD: Clinical Characteristics, an Operational “Cluster Phase,” and Potential Strategies to Prevent Therapeutic Gaps

2026-04-07

Abstract excerpt

<title>Abstract</title> <p>Background: Neuromyelitis optica spectrum disorder (NMOSD) can cause severe neurological disability after a single relapse. Although relapse rates have markedly decreased with the emergence of targeted biologics, treatment switches are increasingly encountered due to long-term treatment considerations and adverse events. However, safe switching strategies, especially within 12 months a...

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Literature Corpus work
6d1794fd-3b8e-5326-b355-fef17dac7264
DOI
10.21203/rs.3.rs-9158568/v1
Open publication

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Switching from Complement Inhibitors in AQP4-IgG–Positive NMOSD: Clinical Characteristics, an Operational “Cluster Phase,” and Potential Strategies to Prevent Therapeutic GapsDOI 10.21203/rs.3.rs-9158568/v1
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