Article
Serum AQP4-IgG level is associated with the phenotype of the first attack in neuromyelitis optica spectrum disorders.
Journal of neuroimmunology - 15 Mar 2020
Akaishi Tetsuya, Takahashi Toshiyuki, Himori Noriko, Fujihara Kazuo, Misu Tatsuro, Abe Michiaki, Ishii Tadashi, Nakazawa Toru, Aoki Masashi, Nakashima Ichiro
Abstract excerpt
We aimed in this study to elucidate the impact of serum AQP4-IgG titer before starting treatments to the clinical manifestation of neuromyelitis optica spectrum disorders (NMOSD). Serum titer at the onset, measured using live cell-based assay method, did not correlate to the subsequent relapse rate or neurological prognosis. Patients with optic neuritis as the first attack showed significantly higher serum titer...
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