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The Role of Fusobacterium nucleatum in Colorectal Cancer Cell Proliferation and Migration

30 Oct 2022

Abstract excerpt

Colorectal cancer (CRC) is a common cancer worldwide with poor prognosis. The presence of Fusobacterium nucleatum (Fn) in the intestinal mucosa is associated with the progression of CRC. In this review, we explore the mechanisms by which Fn contributes to proliferation and migration of CRC cells from the following four aspects: induction of the epithelial–mesenchymal transition (EMT), regulation of the tumor...

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PMID: 36358769
DOI: 10.3390/cancers14215350

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