Article

SmartImpute: A Targeted Imputation Framework for Single-cell Transcriptome Data

2024-07-18

Abstract excerpt

<h4>ABSTRACT</h4> Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular heterogeneity and tissue transcriptomic complexity. However, the high frequency of dropout events in scRNA-seq data complicates downstream analyses such as cell type identification and trajectory inference. Existing imputation methods address the dropout problem but face limitations such as high computational...

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Literature Corpus work: 6cd42a31-9d80-5539-abc5-f55e6455b3c0
DOI: 10.1101/2024.07.15.603649

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