Article

SpaGene: A Deep Adversarial Framework for Spatial Gene Imputation

2025-10-06

Abstract excerpt

<h4>ABSTRACT</h4> Integrating transcriptome-wide single-cell gene expression data with spatial context significantly enhances our understanding of tissue biology, cellular interactions, and disease progression. Although single-cell RNA sequencing (scRNA-seq) provides high-resolution gene expression data, it lacks crucial spatial context, whereas spatial transcriptomics techniques offer spatial resolution but are...

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Literature Corpus work: 2f521fb7-7486-5a46-a893-1cf29f9ee127
DOI: 10.1101/2025.10.03.680242

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