Article

A phase 2 open-label clinical trial to determine the effect of Famciclovir on Epstein-Barr virus activity as measured by EBV shedding in the saliva of patients with Multiple Sclerosis

2023-08-20

Abstract excerpt

<h4>Background</h4> There is increasing evidence that Epstein-Barr virus (EBV) plays a causal role in MS. No treatments have been shown to reduce EBV turnover. We studied the effect of famciclovir on salivary EBV shedding in people with MS ( NCT05283551 ). <h4>Methods</h4> People with MS receiving natalizumab provided weekly saliva samples for 12 weeks before starting Famciclovir 500mg bd. 12 saliva samples were p...

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Literature Corpus work: 6ca7d086-1c3d-5916-8853-61763680e485
DOI: 10.1101/2023.08.18.23294265

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