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Epstein-Barr virus is present in the brain of most cases of multiple sclerosis and may engage more than just B cells

2 Feb 2018

Abstract excerpt

Multiple sclerosis (MS) is a chronic neuroinflammatory condition of the central nervous system (CNS). It is a major cause of neurological disability in young adults, particularly women. What triggers the destruction of myelin sheaths covering nerve fibres is unknown. Both genetic and infectious agents have been implicated. Of the infectious agents, Epstein-Barr virus (EBV), a common herpesvirus, has the strongest...

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PMID: 29394264
DOI: 10.1371/journal.pone.0192109

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