Article

Drug target prediction through deep learning functional representation of gene signatures

2023-09-28

Abstract excerpt

<title>Abstract</title> <p>Many machine learning applications in bioinformatics currently rely on gene identities extracted from input gene signatures, and fail to take advantage of preexisting knowledge about gene functions. We developed the Functional Representation of Gene Signatures (FRoGS) approach by training a deep learning model. FRoGS represents gene signatures projected onto their biological functions,...

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Literature Corpus work: 6c63f33b-a920-5fbd-85cc-61f1e05fea54
DOI: 10.21203/rs.3.rs-3371688/v1

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