Article

Targeting glucocorticoid-induced CD20 activation in preclinical models of B-ALL

2025-12-18

Abstract excerpt

Pediatric B-cell acute lymphoblastic leukemia (B-ALL) is effectively controlled with contemporary multi-agent chemotherapy, resulting to 5-year survival rates above 90%. However, relapse occurs in 15-20% of patients due to minimal residual disease (MRD), characterized by the presence of persisting and resistant leukemic cells, and associated with a poor clinical outcome. Despite its prognostic relevance, the molec...

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Literature Corpus work: 6c4204de-c163-5443-9711-1e68caaa37a0
DOI: 10.64898/2025.12.16.694550

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