Article

Genetically encoded green fluorescent biosensors for monitoring UDP-GlcNAc in live cells

2021-06-23

Abstract excerpt

Uridine diphosphate N -acetylglucosamine (UDP-GlcNAc) is a nucleotide sugar used by glycosyltransferases to synthesize glycoproteins, glycosaminoglycans, glycolipids, and glycoRNA. UDP-GlcNAc also serves as the donor substrate for the formation of O -GlcNAc, a dynamic intracellular protein modification involved in diverse signaling and disease processes. UDP-GlcNAc is thus a central metabolite connecting nutriti...

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Literature Corpus work: 6c1d6572-9749-5bc9-b904-5bfe5d2e37d6
DOI: 10.1101/2021.06.23.449603

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