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Integrated Genomic Profiling Identifies Predictive Biomarkers for Neoadjuvant Therapy Response in Chinese Breast Cancers

2025-07-29

Abstract excerpt

<title>Abstract</title> <p> Background Neoadjuvant therapy (NAT) has emerged as a standard treatment strategy for locally advanced breast cancer (BC), yet effective predictive markers are still lacking. Methods We constructed a large-scale NAT cohort of 1,161 primary BC patients, including 1,145 cases with paired clinicopathological data and targeted sequencing, to identify biomarkers of NAT efficacy. Results Sy...

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Literature Corpus work
6c124c53-22fe-57b9-9837-d37a21566f88
DOI
10.21203/rs.3.rs-7055446/v1
Open publication

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Integrated Genomic Profiling Identifies Predictive Biomarkers for Neoadjuvant Therapy Response in Chinese Breast CancersDOI 10.21203/rs.3.rs-7055446/v1
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