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Article

Genetic mutation profile of Chinese HER2-positive breast cancers and genetic predictors of responses to Neoadjuvant anti-HER2 therapy.

Breast cancer research and treatment - 1 Sept 2020

Li Kai, Liao Ning, Chen Bo, Zhang Guochun, Wang Yulei, Guo Liping, Wei Guangnan, Jia Minghan, Wen Lingzhu, Ren Chongyang, Cao Li, Mok Hsiaopei, Li Cheukfai, Lin Jiali, Chen Xiaoqing, Zhang Zhou, Hou Ting, Li Min, Liu Jing, Balch Charles M, Liao Ning

Abstract excerpt

PURPOSE: Despite the therapeutic success of existing HER2-targeted therapies, tumors respond quite differently to them. This study aimed at figuring out genetic mutation profile of Chinese HER2-positive patients and investigating predictive factors of neoadjuvant anti-HER2 responses. METHODS: We employed two cohorts. The first cohort was comprised of 181 HER2-positive patients treated at Guangdong Provincial...

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Identifiers

PMID: 32638235
DOI: 10.1007/s10549-020-05778-0
PMCID: PMC7383038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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