Article

Decoding the activated stem cell phenotype of the vividly maturing neonatal pituitary

2022-01-20

Abstract excerpt

The pituitary represents the endocrine master regulator. In mouse, the gland undergoes vivid maturation immediately after birth. Here, we in detail portrayed the stem cell compartment of neonatal pituitary. Single-cell RNA-sequencing pictured an active gland, revealing proliferative stem as well as hormonal (progenitor) cell populations. The stem cell pool displayed a hybrid epithelial/mesenchymal phenotype, chara...

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Literature Corpus work: 6bbb0108-8778-56c0-a10d-8edd572a7c8c
DOI: 10.1101/2022.01.18.476723

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