Article
SERCA2a gene therapy as an anti-arrhythmic in patients with advanced heart failure
2017-01-01
Abstract excerpt
Despite advances in pharmacological therapy, mortality and morbidity in heart failure remain high. Numerous underlying molecular abnormalities exist in the failing myocycte, of particular importance are those leading to deranged calcium handling. Gene therapy is an approach that can target these molecular abnormalities directly and a target that has received significant interest is sarcoplasmic (endoplasmic) retic...
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Identifiers and source
- Literature Corpus work
- 6b74400f-ff17-5967-9253-fbe5413f5c73
- DOI
- 10.25560/53129