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Article

Restoration of β-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer

28 Oct 1997

Abstract excerpt

Cardiovascular gene therapy is a novel approach to the treatment of diseases such as congestive heart failure (CHF). Gene transfer to the heart would allow for the replacement of defective or missing cellular proteins that may improve cardiac performance. Our laboratory has been focusing on the feasibility of restoring beta-adrenergic signaling deficiencies that are a characteristic of chronic CHF. We have now...

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Identifiers

PMID: 9342369
DOI: 10.1073/pnas.94.22.12100

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Source receipt: pubmed, retrieved 7 Sept 2026.

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