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Article

Targeting calcium cycling proteins in heart failure through gene transfer

1 Jan 2003

Abstract excerpt

Our understanding of cardiac excitation-contraction coupling has improved significantly over the last 10 years. Furthermore, defects in the various steps of excitation-contraction coupling that characterize cardiac dysfunction have been identified in human and experimental models of heart failure. The various abnormalities in ionic channels, transporters, kinases and various signalling pathways collectively...

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Identifiers

PMID: 12509478
DOI: 10.1113/jphysiol.2002.026732

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