Article

Multistage Machine Learning Reveals Circadian Gene Programs and Supports a Retina–Choroid Axis in Myopia Development

2026-04-06

Abstract excerpt

<h4>Purpose</h4> To determine whether circadian timing defines critical molecular windows in myopia development and to assess the transferability of circadian gene programs across ocular tissues, disease stages, and species. <h4>Methods</h4> Publicly available retinal and choroidal RNA-seq datasets from chick models of form-deprivation myopia were analyzed using unsupervised transcriptomic profiling and multista...

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Literature Corpus work: 6b66dbad-a8c9-5470-9ed2-baa1990f4a4a
DOI: 10.64898/2026.04.02.716020

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