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Article

Bidirectional Expression of Metabolic, Structural, and Immune Pathways in Early Myopia and Hyperopia

30 Aug 2016

Abstract excerpt

Myopia (short-sightedness) affects 1.45 billion people worldwide, many of whom will develop sight-threatening secondary disorders. Myopic eyes are characterized by excessive size while hyperopic (long-sighted) eyes are typically small. The biological and genetic mechanisms underpinning the retina's local control of these growth patterns remain unclear. In the present study, we used RNA sequencing to examine gene...

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PMID: 27625591
DOI: 10.3389/fnins.2016.00390

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