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Article

Why patients with familial hypercholesterolemia are at high cardiovascular risk? Beyond LDL-C levels.

Trends in cardiovascular medicine - 1 May 2021

Bianconi Vanessa, Banach Maciej, Pirro Matteo

Abstract excerpt

Familial hypercholesterolemia (FH) is a common genetic cause of elevated low-density lipoprotein cholesterol (LDL-C) due to defective clearance of circulating LDL particles. All FH patients are at high risk for premature cardiovascular disease (CVD) events due to their genetically determined lifelong exposure to high LDL-C levels. However, different rates of CVD events have been reported in FH patients, even...

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Identifiers

PMID: 32205033
DOI: 10.1016/j.tcm.2020.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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