Article

Single-Cell RNA sequencing reveals altered microenvironment and pro-tumoral effects of TLE4 within invasive somatotroph adenoma

2022-10-20

Abstract excerpt

<h4>Background: </h4> Invasive somatotroph adenoma, a dominant subtype of pituitary adenoma (PA), is considered a clinical challenge with limited treatments other than surgery. Single-cell transcriptome analysis provides the opportunity to characterize the cellular composition of the tumor microenvironment (TME) and elucidate the potential origin of PA cells and the mechanisms of tumor progression. <h4>Methods: <...

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Literature Corpus work: 6b28081a-6120-55e6-b11c-a0368d398d65
DOI: 10.21203/rs.3.rs-2145299/v1

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