Article

Consuming Genistein Improves Survival Rates in the Absence of Laxative in Δf508-Cf Female Mice

2018-08-04

Abstract excerpt

Genistein is a naturally occurring isoflavone found in soy. Mice homozygous for the ∆F508 mutation are characterized with severe intestinal disease and require constant laxative treatment for survival. This pathology mimics the intestinal obstruction (meconium ileus) seen in some cystic fibrosis (CF) patients. We therefore tested whether dietary supplementation with genistein would reduce the dependence of the ∆F5...

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Literature Corpus work: 6ad4fe05-eb40-53f1-83b0-b99644d84f95
DOI: 10.20944/preprints201808.0084.v1

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