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Article

Genistein is an Efficient Estrogen in the Whole-Body throughout Mouse Development

14 Feb 2008

Abstract excerpt

The widespread use of diets containing estrogenic compounds raises questions on how relevant the presence of phytoestrogens may be, in order to allow a correct development of the reproductive ability and sexual maturity in humans and animals. The isoflavone genistein is the most estrogenically active molecule present in soy. Here we show that genistein, through an estrogen receptor (ER)-mediated action, modulates...

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Identifiers

PMID: 18281260
DOI: 10.1093/toxsci/kfn021

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