Article

SETD2 Deficiency and miR-21: Potent Therapeutic Targets in NUT Midline Carcinoma

2021-09-20

Abstract excerpt

<h4>Background: </h4> Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare and highly aggressive tumor with the bromodomain containing 4 protein ( BRD4 ) -NUT ( NUTM1 ) gene fusion. Few targeted therapies are available for NMC, and novel therapeutic targets are required. The objectives of our study was to determine gene mutations and microRNA (miRNA) expression levels in NMC and to identify novel ther...

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Literature Corpus work: 6acc5543-e920-584a-b9c4-fd268f0f8de3
DOI: 10.21203/rs.3.rs-857889/v1

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