Article

SETD2 and miR-21 as therapeutic targets for NUT midline carcinoma

2021-03-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold>Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare and highly aggressive tumor with the bromodomain containing 4 (<italic>BRD4</italic>)<italic>-NUT</italic> (<italic>NUTM1</italic>) gene fusion. BRD4 is a member of the bromodomain and extra-terminal domain (BET) family of proteins, and BET inhibitors have been investigated in NMC clinical trials....

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Literature Corpus work: a01925c2-361c-5f65-a9b5-51de4228acfc
DOI: 10.21203/rs.3.rs-286917/v1

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