Article

Shifts in microbial transcription patterns prior to onset of <i>Necrotizing enterocolitis</i> may indicate low oxygen levels in the gut

2018-11-09

Abstract excerpt

<h4>Summary</h4> Premature infants are at risk for developing necrotizing enterocolitis (NEC), an inflammatory disease that can progress to necrosis of gut tissue. Previous attempts have failed to identify any consistent predictor of NEC. We hypothesized that prior to the appearance of NEC symptoms, the gut microbiome shifts in its transcriptional profile. To test this hypothesis we integrated genome-resolved me...

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Literature Corpus work: 6abc8d73-87ea-5841-83d1-a845d639c5c3
DOI: 10.1101/466417

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