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Necrotizing enterocolitis is preceded by increased gut bacterial replication, <i>Klebsiella</i> , and fimbriae-encoding bacteria that may stimulate TLR4 receptors

2019-02-22

Abstract excerpt

Necrotizing enterocolitis (NEC) is a devastating intestinal disease that occurs primarily in premature infants. We performed genome-resolved metagenomic analysis of 1,163 fecal samples from premature infants to identify microbial features predictive of NEC. Features considered include genes, bacterial strain types, eukaryotes, bacteriophages, plasmids and growth rates. A machine learning classifier found that samp...

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Literature Corpus work
db2a3552-705f-54e4-a32e-97ec013a74a7
DOI
10.1101/558676
Open publication

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