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Article

Early microbial and metabolomic signatures predict later onset of necrotizing enterocolitis in preterm infants

15 Apr 2013

Abstract excerpt

BACKGROUND: Necrotizing enterocolitis (NEC) is a devastating intestinal disease that afflicts 10% of extremely preterm infants. The contribution of early intestinal colonization to NEC onset is not understood, and predictive biomarkers to guide prevention are lacking. We analyzed banked stool and urine samples collected prior to disease onset from infants <29 weeks gestational age, including 11 infants who...

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PMID: 24450576
DOI: 10.1186/2049-2618-1-13

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