Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling

Abstract excerpt

The gut microbiome is significantly altered in inflammatory bowel diseases, but the basis of these changes is not well understood. We have combined metagenomic and metatranscriptomic profiling of the gut microbiome to assess modifications to both bacterial community structure and transcriptional activity in a mouse model of colitis. By using transcriptomic analysis of colonic tissue and luminal RNA derived from...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gut microbiota and health
• Share to Helicobacter pylori-related gastroenterology studies
• Share to Immune Response and Inflammation