Article
Correlation between miRNA-targeted-gene promoter methylation and miRNA regulation of target genes
2013-09-11
Abstract excerpt
<h4>Background: </h4> miRNA regulation of target genes and promoter methylation are known to be the primary mechanisms underlying the epigenetic regulation of gene expression. However, how these two processes cooperatively regulate gene expression has not been extensively studied. <h4>Methods: </h4> Gene expression and promoter methylation profiles of 270 distinct human cell lines were obtained from Gene Expressi...
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Identifiers and source
- Literature Corpus work
- 6ab38e78-a93d-51b2-8685-77ae2b47e573
- DOI
- 10.12688/f1000research.2-21.v3
