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Maternal total sleep deprivation causes oxidative stress and mitochondrial dysfunction in oocytes associated with fertility decline in mice

2024-06-15

Abstract excerpt

Previous studies have shown sleep deprivation has an impact on several aspects of health and disease. Sleep deprivation suppresses melatonin production and excessive HPA activation in women, which may reduce the chances of fertility. However, little is known about how and by what relevant mechanisms it affects female fertility. In this study, female mice underwent 72 hours of total sleep deprivation (TSD) caused b...

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Literature Corpus work
6aa1de70-67a3-532b-97a3-5de4b51c9d4a
DOI
10.1101/2024.06.13.598954
Open publication

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Maternal total sleep deprivation causes oxidative stress and mitochondrial dysfunction in oocytes associated with fertility decline in miceDOI 10.1101/2024.06.13.598954
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