Article

Identification and Validation of Aurora Kinase A (AURKA) Involved in the Progression and Imatinib Resistance of Advanced Gastrointestinal Stromal Tumors

2020-09-23

Abstract excerpt

<h4>Background: </h4> Gastrointestinal stromal tumor (GIST) is a common tumor originating from mesenchyme in the alimentary system. GISTs exhibit unique malignant behavior compared to typical carcinomas. Here, we explored genes that drive the progression and imatinib resistance of GISTs by bioinformatic tools and experiments. <h4>Methods: </h4>: We analyzed gene expression profiles of GISTs and identified a key ge...

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Literature Corpus work: 6a9c6041-61d9-54fe-ab2e-920665021966
DOI: 10.21203/rs.3.rs-79473/v1

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