Article

FBXO7, a tumor suppressor in endometrial carcinoma, suppresses INF2-associated mitochondrial division

2022-09-16

Abstract excerpt

Endometrial carcinoma (ECa) is the most common malignant gynecological cancer, with an increased incidence and fatality rate worldwide. Hyperactive INF2-associated mitochondrial division is involved in the occurrence and development of various tumors, including ECa, although the molecular mechanism is unclear. In this study, we confirmed that FBXO7, an E3 ubiquitin ligase, inhibits INF2-associated mitochondrial di...

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Literature Corpus work: 6a45020d-bf2b-539d-811d-a9aa1a3b289c
DOI: 10.21203/rs.3.rs-2032067/v1

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