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Article

FBXO7, a tumor suppressor in endometrial carcinoma, suppresses INF2-associated mitochondrial division.

Cell death & disease - 21 Jun 2023

Zhang Hui, Zhao Yiting, Wang Jie, Li Jinyun, Xia Jingyi, Lin Yan, Zhong Yeling, Cao Xinyi, Jin Jiabei, Li Xinming, Yang Weili, Ye Meng, Jin Xiaofeng

Abstract excerpt

Endometrial carcinoma (ECa) is the most common malignant gynecological cancer, with an increased incidence and fatality rate worldwide, while the pathogenesis is still largely unknown. In this study, we confirmed that FBXO7, a gene coding FBXO7 E3 ubiquitin ligase, is significantly downregulated and mutated (5.87%; 31/528) in ECa specimens, and the abnormal low expression and mutations of FBXO7 are associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37344480
DOI: 10.1038/s41419-023-05891-0
PMCID: PMC10284917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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FBXO7, a tumor suppressor in endometrial carcinoma, suppresses INF2-associated mitochondrial division.PMID 37344480Read ↗

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