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Article

Substance P and adenosine signaling pathways regulate exosomal sorting of miR-21 in colonic epithelial cells

2022-04-05

Abstract excerpt

<h4>Background & Aims</h4> MicroRNAs (miRNAs) are transported in body fluids within exosomes, and exosomal-miRNA sorting is highly selective. In colonic epithelial cells (CECs), Substance P-neurokinin-1-receptor (SP/NK1R) signaling regulates miR-21 sorting into secreted exosomes. Here, we studied the molecular mechanisms driving miR-21 sorting into colonic epithelial exosomes (CEEs) under SP-stimulation. <h4>Meth...

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Literature Corpus work
6a2912e9-4ed9-5bdc-abe0-efee6c2adf56
DOI
10.1101/2022.03.30.486482
Open publication

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Substance P and adenosine signaling pathways regulate exosomal sorting of miR-21 in colonic epithelial cellsDOI 10.1101/2022.03.30.486482
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