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Plasma exosomal miR-199a-3p downregulates cell proliferation and migration in Hirschsprung’s disease by targeting mTOR

2022-10-10

Abstract excerpt

<h4>Background: </h4> Plasma exosomal microRNAs have been suggested to be potential biomarkers of disease. However, the exosomal microRNAs in Hirschsprung’s disease (HSCR) are still unclear. In this study, we analyzed the miRNA profiles of HSCR and elucidated the mechanism of the selected miR-199a-3p in the development of HSCR. Methods Plasma exosomes were isolated, and exosomal miRNA high-throughput sequencing w...

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Literature Corpus work
d5ac0a4b-c050-5da4-8a90-e1923325112a
DOI
10.21203/rs.3.rs-2126163/v1
Open publication

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