Article

Cardiac Sex Differences are Established Prior to Gonad Formation

2020-10-01

Abstract excerpt

<h4>ABSTRACT</h4> Male and female disease states differ in their prevalence, treatment responses, and survival rates. In cardiac disease, women almost uniformly fare far worse than men. Though sex plays a critical role in cardiac disease, the mechanisms underlying sex differences in cardiac homeostasis and disease remain unexplained. Here, in adult and embryonic hearts we reveal sex-specific transcriptomes and pr...

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Literature Corpus work: 1c72cf6f-1ac0-5544-9c8e-fbd2f7cb4aec
DOI: 10.1101/2020.09.29.319194

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