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Sex Differences in Skeletal Muscle Pathology in Patients With Heart Failure and Reduced Ejection Fraction

1 Oct 2024

Abstract excerpt

BACKGROUND: Women with heart failure and reduced ejection fraction (HFrEF) have greater symptoms and a lower quality of life compared with men; however, the role of noncardiac mechanisms remains poorly resolved. We hypothesized that differences in skeletal muscle pathology between men and women with HFrEF may explain clinical heterogeneity. METHODS: Muscle biopsies from both men (n=22) and women (n=16) with...

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PMID: 39381880
DOI: 10.1161/circheartfailure.123.011471

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