Article

Leveraging cell type-specificity for gene set analysis of single cell transcriptomics

2024-09-27

Abstract excerpt

Although single cell RNA-sequencing (scRNA-seq) provides unprecedented insights into the biology of complex tissues, analyzing such data on a gene-by-gene basis is challenging due to the large number of tested hypotheses and consequent low statistical power and difficult interpretation. These issues are magnified by the increased noise, significant sparsity and multi-modal distributions characteristic of single ce...

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Literature Corpus work: 6a00619e-5614-5b10-8775-e4b4f14a927f
DOI: 10.1101/2024.09.25.615040

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