Article

Knockout of miR-17-92 Cluster Protect Against Intervertebral Disc Degeneration by Inhibiting Apoptosis of Nucleus Pulposus Cells in Mice via the Activation of PI3K/Akt Pathway

2021-04-23

Abstract excerpt

<h4>Background: </h4> microRNA( miR)-17-92 cluster is involved in a variety of physiological and pathological processes, and the purpose of this study is to preliminarily explore the role of miR-17-92 cluster in disc degeneration and the corresponding mechanisms. <h4>Methods: </h4>: Hematoxylin and Eosin (HE) and Safranin O Staining were used to evaluate the degeneration of intervertebral disc. qRT-PCR was applied...

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Literature Corpus work: 69f75c1b-92e8-539f-ab8f-688e97322946
DOI: 10.21203/rs.3.rs-436505/v1

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