Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

tsRNA-04002 alleviates intervertebral disk degeneration by targeting PRKCA to inhibit apoptosis of nucleus pulposus cells

7 Jun 2023

Abstract excerpt

BACKGROUND: Intervertebral disk degeneration (IDD) is a degenerative disease that underlies various musculoskeletal and spinal disorders and is positively correlated with age. tRNA-derived small RNAs (tsRNA), as a new small noncoding RNAs, its function in IDD is unclear. Herein, our goal was to find the key tsRNA that affects IDD independently of age and explore the underlying mechanisms. METHODS: Small RNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Orthopaedic implants and arthroplasty
Share to Spine and Intervertebral Disc Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37287061
DOI: 10.1186/s13018-023-03878-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

tsRNA-04002 alleviates intervertebral disk degeneration by targeting PRKCA to inhibit apoptosis of nucleus pulposus cellsPMID 37287061Read ↗

The potential mechanisms and application prospects of non-coding RNAs in intervertebral disc degenerationSemantic proximity Read ↗

The role of miRNA, lncRNA and circRNA in the development of intervertebral disk degeneration (Review)Semantic proximity Read ↗

The Mechanism and Function of <scp>miRNA</scp> in Intervertebral Disc DegenerationSemantic proximity Read ↗

Role of microRNAs in intervertebral disc degeneration (Review)Semantic proximity Read ↗

Long non-coding RNA HOTAIR modulates intervertebral disc degenerative changes via Wnt/β-catenin pathwaySemantic proximity Read ↗

Circular RNA hsa_circ_0001658 Inhibits Intervertebral Disc Degeneration Development by Regulating hsa-miR-181c-5p/FASSemantic proximity Read ↗

miR‐328‐5p Induces Human Intervertebral Disc Degeneration by Targeting WWP2Semantic proximity Read ↗

Profiling and bioinformatics analysis of differentially expressed circular RNAs in human intervertebral disc degenerationSemantic proximity Read ↗

Long non‐coding RNA s in nucleus pulposus cell function and intervertebral disc degenerationSemantic proximity Read ↗

Circular RNAs in nucleus pulposus cell function and intervertebral disc degenerationSemantic proximity Read ↗

Long non-coding RNA PART1 promotes intervertebral disc degeneration through regulating the�miR‑93/MMP2 pathway in nucleus pulposus cellsSemantic proximity Read ↗

Aberrantly expressed long noncoding RNAs in human intervertebral disc degeneration: a microarray related studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.