Article

A dividing cell model for stable propagation and curing of <i>bona fide</i> human sporadic Creutzfeldt-Jakob Disease prions

2025-11-26

Abstract excerpt

Prions are assemblies of misfolded proteins that cause transmissible, progressive neurodegenerative disease in humans and other mammals. Human prion diseases have particular public health and biological significance, both due to their transmissibility between hosts, and the mechanisms they share with many other neurodegenerative conditions. However, their study has been considerably impeded by the absence of a cel...

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Literature Corpus work: 69e5640f-4c24-5bef-8e09-ffc81119a31c
DOI: 10.1101/2025.11.23.690013

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