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Article

ALS Genes in the Genomic Era and their Implications for FTD.

Trends in genetics : TIG - 1 Jun 2018

Nguyen Hung Phuoc, Van Broeckhoven Christine, van der Zee Julie

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease, characterized genetically by a disproportionately large contribution of rare genetic variation. Driven by advances in massive parallel sequencing and applied on large patient-control cohorts, systematic identification of these rare variants that make up the genetic architecture of ALS became feasible. In this review paper, we present a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29605155
DOI: 10.1016/j.tig.2018.03.001

Genes

ANXA11
CCNF
CHCHD10
MATR3
NEK1
TBK1
TIA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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