Article

Integrin-driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program

2021-12-07

Abstract excerpt

<h4>ABSTRACT</h4> The peripheral branch of sensory dorsal root ganglion (DRG) neurons regenerates readily after injury unlike their central branch in the spinal cord. However extensive regeneration and reconnection of sensory axons in the spinal cord can be driven by the expression of α9 integrin and its activator kindlin- 1(α9k1), which enable axons to interact with tenascin-C. To elucidate the mechanisms and do...

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Literature Corpus work: 44d07b23-4aaa-5765-bdb3-4d8329e2fa48
DOI: 10.1101/2021.12.07.471602

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