Article

Mitochondrial sirtuin TcSir2rp3 affects TcSODA activity and oxidative stress response in <i>Trypanosoma cruzi</i>

2021-09-06

Abstract excerpt

Trypanosoma cruzi , the etiological agent of Chagas disease, faces a variety of environmental scenarios during its life cycle in both invertebrate and vertebrate hosts, which include changes in the redox environment that requires a fine regulation of a complex antioxidant arsenal of enzymes. Reversible post-translational modifications, as lysine acetylation, are a fast and economical way for cells to react to envi...

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Literature Corpus work: 6982a67e-5a0a-5ce5-a195-fa1fc19712f3
DOI: 10.1101/2021.09.06.458705

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